Apolipoprotein E Deficiency Aggravates Neuronal Injury by Enhancing Neuroinflammation via the JNK/c-Jun Pathway in the Early Phase of Experimental Subarachnoid Hemorrhage in Mice

Figure 4

APOE deficiency aggravated microglial activation. (a) SAH increased the number of microglia in the cortex and white matter (, , compared to sham, ), while more microglia increased in APOE^-/- mice than in WT mice (^##). (b) Western blotting showing overexpression of Iba-1 after SAH (, , compared to sham, ). APOE^-/- mice exhibited higher Iba-1 level than WT mice (^##). .

(a)

(b)