Upregulation of Transient Receptor Potential Canonical Type 3 Channel via AT1R/TGF-<i>β</i>1/Smad2/3 Induces Atrial Fibrosis in Aging and Spontaneously Hypertensive Rats

<div>The summary of the signaling pathway of TRPC3 upregulation in fibroblasts involved in fibrosis. The blue signaling pathway is evidenced by this study, and the red and green ones were reported by published papers.</div>

Oxidative Medicine and Cellular Longevity

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Figure 10

Figure 10: Upregulation of Transient Receptor Potential Canonical Type 3 Channel via AT1R/TGF-<i>β</i>1/Smad2/3 Induces Atrial Fibrosis in Aging and Spontaneously Hypertensive Rats 

Figure 10 | Upregulation of Transient Receptor Potential Canonical Type 3 Channel via AT1R/TGF-β1/Smad2/3 Induces Atrial Fibrosis in Aging and Spontaneously Hypertensive Rats 