Oxidative Medicine and Cellular Longevity / 2019 / Article / Fig 3

Research Article

Upregulation of Transient Receptor Potential Canonical Type 3 Channel via AT1R/TGF-β1/Smad2/3 Induces Atrial Fibrosis in Aging and Spontaneously Hypertensive Rats

Figure 3

Upregulation of fibrotic biomarkers and TRPC3 in the atrium from SHR and WKY with aging. The relative mRNA and protein expressions of collagen I (left, upper panel, COL-I) (a), collagen III (right, upper panel, COL-III) (b), TGF-β1 (left, bottom panel) (c), and TRPC3 (right, bottom panel) (d). All values are presented as the of 8 rats. and significantly different compared with WKY 4m-o.

Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.