Green Tea Prevents NAFLD by Modulation of miR-34a and miR-194 Expression in a High-Fat Diet Mouse Model

Figure 2

Green tea has hepatoprotective effects in HFD-induced NAFLD. (a) Liver histological analysis, (b) activity score of NAFLD, (c) distribution of macrovesicular steatosis, (d, e) hepatic triglyceride content and cholesterol, (f, g) ALT and AST plasma activity, and (h) analysis of expression of the genes involved in the inflammatory process, such as Mcr1, Cd86, Tlr, Traf6, Ikbkb, Nfkb, and Tnf. Results are presented as of at least 06 animals per group. ANOVA one- and two-way and Student’s -test were used for all the statistical analysis. When the difference was statistically significant, the following overwritten letters were used: ^aCompared to the Cont group. ^bCompared to the HFD group.

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