Cucurbitacin B Exerts Antiaging Effects in Yeast by Regulating Autophagy and Oxidative Stress
Effect of CuB on oxidative stress in yeast. (a) Effect of CuB on yeast growth with 5 μL yeast culture and 1/10, 1/100, and 1/1000 dilutions under oxidative conditions simulated with 9 mM H2O2. (b) Effect of CuB on the survival rate of yeast under oxidative conditions simulated with 5 mM H2O2. and represent significant differences compared to the control group ( and , respectively). (c, d, e, f) Effect of CuB on ROS level, MDA accumulation, T-Sod, and Sod1 enzyme activity at 24 or 48 h. ,, and #, ##, ### indicate significant differences from the corresponding control (,, and , respectively).
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