Folic Acid Supplementation Suppresses Sleep Deprivation-Induced Telomere Dysfunction and Senescence-Associated Secretory Phenotype (SASP)

<div>Folic acid restrains telomere shortening induced by sleep deprivation. (a) The telomere length of bone marrow cells was detected by quantitative fluorescence in situ hybridization (Q-FISH) and is shown as average fluorescence units (AFUs). Scale bars are 10 <i>μ</i>m. (b) Scatter plot of telomere AFUs for more than 200 cells of all mice. (c) The histogram displays the distribution of relative telomere length as AFUs. 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Oxidative Medicine and Cellular Longevity

fig2

Figure 2

Figure 2: Folic Acid Supplementation Suppresses Sleep Deprivation-Induced Telomere Dysfunction and Senescence-Associated Secretory Phenotype (SASP) 