Research Article
NADPH Oxidase Hyperactivity Contributes to Cardiac Dysfunction and Apoptosis in Rats with Severe Experimental Pancreatitis through ROS-Mediated MAPK Signaling Pathway
Figure 4
Effects of Nox inhibition on cardiac histopathology and cardiac-related enzymes 24 h after SAP induction. Representative micrographs of HE-stained sections of rat heart tissue from different groups; the arrow shows disruptive myocardial fibers. Images were taken under 200x magnification (a). Histology severity score of heart (b). Lactic dehydrogenase-L (LDH-L) (c). Creatine kinase isoenzyme MB (CK-MB) (d). Cardiac troponin I (cTnI) (e). Data are presented as , rats per group. SO, sham operation; SAP, severe acute pancreatitis; SAP-APO, SAP+apocynin; APO-CON, apocynin control. compared with the SO group. compared with the SAP group.
(a) |
(b) |
(c) |
(d) |
(e) |