Research Article
MicroRNA-155 Promotes Myocardial Infarction-Induced Apoptosis by Targeting RNA-Binding Protein QKI
Figure 3
Effect of miR-155 on apoptosis-related protein expression and mitochondrial membrane potential (Δψm). (a) Western blot analysis of relative Bcl-2 protein expression in NRVMs. . (b) Western blot analysis of relative Bax protein expression in NRVMs. . (c) Western blot analysis of relative C-casp3 protein expression in NRVMs. . (d) XIAP expression level was detected by western blot. . (e) Representative fluorescent images of JC-1 monomeric mitochondria showing green fluorescence and JC-1-aggregated mitochondria showing red from control, H2O2, H2O2+NC, and H2O2+AMO-155 groups. (f) Statistical analysis of mitochondrial membrane potential labelled by JC-1 monomeric. . , vs. control; , vs. +NC. +NC: H2O2+NC; +AMO-155: H2O2+AMO-155; C-casp3: cleaved-caspase-3.
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