Signaling Pathways, Chemical and Biological Modulators of Nucleotide Excision Repair: The Faithful Shield against UV Genotoxicity

Figure 3

Posttranslational modifications of NER factors. Several NER factors including XPC, XPB, XPG, XPA, and CSB are subjected to different forms of posttranslational modifications that can either activate them favoring NER enhancement or the direct opposite via their inhibition.