tert-Butylhydroquinone Treatment Alleviates Contrast-Induced Nephropathy in Rats by Activating the Nrf2/Sirt3/SOD2 Signaling Pathway
t-BHQ decreased blood urea nitrogen (a) and serum levels (b) in CIN rats. Rats in the ioversol group were sequentially injected in the tail vein: indomethacin (10 mg/kg), followed by L-NAME (100 mg/kg) and ioversol (2.9 g/kg) 15 and 30 min later. t-BHQ was administered to rats in the t-BHQ+ioversol group. Date was expressed as the . versus the control group; & versus the ioversol group.