tert-Butylhydroquinone Treatment Alleviates Contrast-Induced Nephropathy in Rats by Activating the Nrf2/Sirt3/SOD2 Signaling Pathway
t-BHQ protected against CIN-induced reactive oxygen species in HK-2 cells. (a) ROS level. (b) Malondialdehyde (MDA) level. (c) SOD2 activity. (d) GSH/GSSG ratio. HK-2 cells were infected by si-Nrf2 and then treated with 50 mg/ml ioversol for 24 h to induce oxidative stress. Data were expressed as the . versus si-control; & versus the si-control+ioversol group; # versus the si-control+t-BHQ+ioversol group.