Oxidative Medicine and Cellular Longevity

Research Article

Application of Urinary Polyphenol Biomarkers Measured by Liquid Chromatography Tandem Mass Spectrometry to Assess Polyphenol Intake and Their Association with Overweight and Obesity in Free-Living Healthy Subjects

Table 2

Odds ratios (95% confidence intervals) for overweight/obesity^a.


	Univariable		Multivariable^b
	OR (95% CI)		OR (95% CI)

Age	1.034 (1.007~1.062)	0.015	1.068 (1.016~1.123)	0.010
Female	1.347 (0.603~3.011)	0.468	1.459 (0.239~8.904)	0.682
FBG	5.722 (2.250~14.549)	<0.001	4.063 (1.299~12.710)	0.016
UA	20.619 (6.780~62.707)	0.001	1.007 (0.998~1.017)	0.114
CREA	0.993 (0.966~1.022)	0.646	0.992 (0.938~1.050)	0.791
CRP	1.220 (1.014~1.467)	0.035	1.129 (0.916~1.393)	0.255
IsoP	1.003 (0.999~1.007)	0.143	1.002 (0.998~1.007)	0.354
Hypertension^a	2.394 (0.743~7.714)	0.144	0.653 (0.132~3.224)	0.601
Dyslipidemia^a	4.609 (1.782~11.924)	0.002	8.216 (2.090~32.303)	0.003
Current smoker	0.365 (0.100~1.327)	0.126	0.206 (0.031~1.392)	0.105
Current drinker	0.703 (0.256~1.933)	0.495	1.008 (0.222~4.586)	0.992
High levels of physical activity	0.737 (0.324~1.677)	0.467	0.239 (0.064~0.891)	0.033
Polyphenol-rich diet	1.391 (0.600~3.226)	0.441	1.182 (0.329~4.241)	0.798
score of 22 urinary polyphenol biomarkers as a continuous variable
Per score increment	0.209 (0.056~0.776)	0.019	0.036 (0.004~0.358)	0.005
score of 22 urinary polyphenol biomarkers as a categorical variable
T1	1.0 (referent)	—	1.0 (referent)	—
T2	1.378 (0.555~3.421)	0.489	0.573 (0.158~2.076)	0.397
T3	0.369 (0.124~1.095)	0.073	0.133 (0.027~0.666)	0.014
value for trend	0.090		0.015

FBG: fasting blood glucose; UA: uric acid; CREA: creatinine; CRP: C-reactive protein; IsoP: 8-isoprostane. ^aDefined according to the criteria of metabolic syndrome from Chinese Diabetes Society (CDS) (2004) for Chinese. ^bSet of independent variables: age, gender, FBG, UA, CREA, CRP, IsoP, hypertension, dyslipidemia, smoking and alcohol drinking status, high levels of physical activity, polyphenol-rich diet, and score of 22 urinary polyphenol biomarkers as a continuous or categorical variable.