Pasteurized Orange Juice Rich in Carotenoids Protects Caenorhabditis elegans against Oxidative Stress and β-Amyloid Toxicity through Direct and Indirect Mechanisms

Figure 5

Effect of pasteurized juice from ‘Bahia’ and ‘Cara Cara’ oranges on C. elegans stress resistance and longevity. (a) Survival curves of wild-type (N2) animals under standard laboratory conditions. Worms were treated with either 2% ‘Bahia’ or 2% ‘Cara Cara’ juice beginning at L4. Survival was verified every day at 25°C. compared to respective controls and comparing animals treated with 2% ‘Bahia’ with 2% ‘Cara Cara’ juice by log-rank (Mantel-Cox) test. (b) Survival curves of wild-type (N2) animals under oxidative stress conditions. Worms were treated with either 2% ‘Bahia’ or 2% ‘Cara Cara’ juice beginning at L4 and transferred to plates with 10 mM TBPH. Survival was verified every 3 hours at 20°C. compared to the untreated control group and comparing animals treated with 2% ‘Bahia’ with 2% ‘Cara Cara’ juice by log-rank (Mantel-Cox) test.

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