Pharmacotherapeutics and Molecular Mechanism of Phytochemicals in Alleviating Hormone-Responsive Breast Cancer

Table 1

Molecular docking scores of 38 compounds.

Name	-Cdocker energy (kcal/mol)	-Cdocker interaction energy (kcal/mol)	Pharmacophore features
Curcumin	19.05	55.14	Yes
Capsaicin	29.12	54.54	Yes
Rosmarinic acid	37.47	53.80	Yes
6-Shogaol	38.99	52.98	Yes
Epigallocatechin gallate	20.15	50.63	No
Rosmanol	5.28	48.0	Yes
Epicatechin	32.40	47.65	No
Piperine	2.96	46.51	Yes
Carnosol	6.18	45.69	Yes
Quercetin	30.21	43.13	No
Resveratrol	29.11	42.74	No
Carnosic acid	1.59	41.87	Yes
Chalcone	30.68	41.62	No
Propyl gallate	44.10	40.87	Yes
Flavanone	29.83	37.69	Yes
Ascorbic acid	19.43	37.55	No
Caffeic acid	36.44	37.31	No
Flavone	28.59	36.43	No
Clove	36.51	36.15	No
p-Coumaric acid	32.43	35.36	No
Flavonol	30.12	34.97	No
Anthocyanin	13.40	32.56	No
Gallic acid	35.02	32.46	No
Protocatechuic acid	32.35	31.93	No
Eugenol	21.98	31.72	Yes
Myristicin	1.55	31.60	Yes
Cinnamaldehyde	26.41	30.94	No
Epicatechin gallate	4.15	30.93	Yes
Carvacrol	29.07	30.78	No
Menthol	20.40	30.76	Yes
α-Terpineol	1.94	30.76	Yes
Thymol	26.70	28.78	No
1,8-Cineol	1.392	26.51	No
Safrole	0.38	25.1	Yes
p-Cymene	24.31	25.08	No
Ascorbyl palmitate	44.20	18.61	Yes
Letrozole	10.71	20.03	Yes
Exemestane	63.35	16.86	Yes