Overexpression of Ras-Related C3 Botulinum Toxin Substrate 2 Radiosensitizes Melanoma Cells In Vitro and In Vivo

Figure 2

The effects of RAC2 on the ROS yield and NADPH oxidase activity of the 4 cell lines exposed to 2 Gy X-rays or 2 Gy carbon ion beams. (a) The ROS yields in the 4 cell lines were measured after X-ray exposure. (b) NADPH consumption in the 4 cell lines after X-ray exposure. (c) The ROS yields in the 4 cell lines were measured after carbon ion beam exposure. (d) NADPH consumption in the 4 cell lines after carbon ion beam exposure. , , and .

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