Overexpression of Ras-Related C3 Botulinum Toxin Substrate 2 Radiosensitizes Melanoma Cells In Vitro and In Vivo
Overexpression of RAC2 enhanced melanoma cell radiosensitivity in vivo. (a) Representative image of tumors generated by OCM-NC or OCM-RAC2 cells in nude mice 1 month post 8 Gy X-ray irradiation. (b) Growth curves of OCM-NC and OCM-RAC2 tumors (). (c) Xenografted tumors collected for weighing. (d) The weights of the xenografted tumors from different groups were compared. (e) H&E staining of the xenografted tunors as well as IHC staining of RAC2 and Bax in xenografted tumors.
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