Encapsulated Mulberry Fruit Extract Alleviates Changes in an Animal Model of Menopause with Metabolic Syndrome

Table 1

Phenolic compound content and biological activity of mulberry fruit extract (ME) and encapsulated mulberry fruit extract (MME).

Parameters	Units	ME-50% hydroalcoholic	MME	Standard reference
Total phenolic	mg GAE/mg extract			—
Total flavonoids	μg quercetin/mg extract			—
Cyanidin 3-glucoside	μg Cyn-3-glu/200 mg extract			—
Quercetin 3-O-rutinoside (rutin)	μg quercetin-3-O-rutinoside/200 mg extract			—
Gallic acid	μg gallic/200 mg extract			—
Antioxidant activities
DPPH	(mg/ml)	0.43 ± 0.05	0.04 ± 0.01	0.03 ± 0.01, ascorbic acid
FRAP	(mg/ml)			122.19 ± 12.82, ascorbic acid
ABTS	(mg/ml)			, Trolox
Antidiabetic markers
α-Amylase inhibition	(mg/ml)			—
α-Glucosidase inhibition	(mg/ml)			—
Aldose reductase inhibition	(mg/ml)			, quercetin
Cardiovascular marker
ACE inhibition	(mg/ml)			, Captopril
Obesity marker
Lipase inhibition	(mg/ml)			, Orlistat
Inflammatory marker
COX-2 inhibition	(mg/ml)			, Indomethacin

Data are presented as . Values are statistically significantly different by Student’s t test compared between MME and mulberry fruit extract. (, and 0.01, respectively).