DpdtbA-Induced Growth Inhibition in Human Esophageal Cancer Cells Involved Inactivation of the p53/EGFR/AKT Pathway

Figure 2

Effect of DpdtbA on cell cycle in ESC cells. Cell cycle distribution of ESC cells following treatment with various concentrations of DpdtbA. (a) Kyse 450 cells and (b) Kyse 150 cells; dose-dependent accumulation in the S phase of the cell cycle. Accordingly, the proportions of cells in the G1 and G2/M phases were decreased.

(a)

(b)