DpdtbA-Induced Growth Inhibition in Human Esophageal Cancer Cells Involved Inactivation of the p53/EGFR/AKT Pathway

Figure 5

DpdtbA induced ROS generation. Flow cytometry analysis from Kyse 450 cells stained by DCF: (a) DMSO; (b) 5 μM DpdtbA; (c) 10 μM DpdtbA; (d) quantitative analysis of ROS production (from twice measurements); (e) western blotting analyses of ferritinophagy-related proteins, the condition was as indicated; (f) the effect of DpdtbA on SOD activity (from trice measurements); (g) alteration of the SOD expression in the absence or presence of DpdtbA; (h) quantitative analysis of alteration in the level of SOD (from twice measurements). .

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