DpdtbA-Induced Growth Inhibition in Human Esophageal Cancer Cells Involved Inactivation of the p53/EGFR/AKT Pathway

Figure 8

p53 downregulation was associated with EGFR and AKT downregulation. (a) Western blotting analysis in the given condition; (b) quantitative analyses of alteration of EGFR, p53, and AKT in the presence or absence of PFT-α (from twice measurements). (c) DpdtbA-induced growth inhibition correlated with p53 downregulation. And the quantitative analysis was based on quartic measurements. ^##, ^,###,$$$.

(a)

(b)

(c)