Early Kidney Damage Markers after Deferasirox Treatment in Patients with Thalassemia Major: A Case-Control Study

Table 2

Comparison of urinary renal parameters in case and control groups.

Variables	Study groups
	Deferoxamine	Deferasirox	Control
	Mean ± SD	Mean ± SD	Mean ± SD	value
U. NGAL				<0.001
U. KIM-1				>0.05
U. IL-18				<0.05
U. CREA				>0.05
U. Alb				<0.05
Urinary NGAL/CREA				<0.05
Urinary IL-18/CREA				>0.05
Urinary KIM-1/CREA				<0.05
Urinary Alb/CREA				>0.05

Kruskal-Wallis test; NGAL: neutrophil gelatinase-associated lipocalin; KIM-1: Kidney Injury Molecule-1; IL: interleukin; CREA: creatinine; Alb: albumin; U: urinary.