Oxidative Medicine and Cellular Longevity

Clinical Study

Additional Effects of Nutritional Antioxidant Supplementation on Peripheral Muscle during Pulmonary Rehabilitation in COPD Patients: A Randomized Controlled Trial

Table 4

Confounding factors during the study of the randomized study population.


	PR placebo group ()	PR antioxidant group ()	value

Systemic corticosteroid treatment	8/18 (31%)	2/29 (6%)	0.02
Duration of corticosteroid treatment (days)			0.33

Antioxidant/placebo supplementation
Duration (days)			0.59
Capsule consumption ()			0.91
Compliance (%)			0.37

Exercise training intensity
at VT/pred. (%)			0.44
Number of exercise training sessions
(i) stationary cycling			0.83
(ii) walking			0.39
(iii) strength building			0.70
(iv) adapted physical activity			0.11

Daily micronutrient intake
Vitamin C (mg/d)			0.46
Vitamin C (%RDA)	%	%	0.46
Vitamin E (mg/d)			0.56
Vitamin E (%RDA)	%	%	0.56
Zinc (mg/d)			0.79
Zinc (%RDA)	%	%	0.79
Copper (mg/d)			0.60
Copper (%RDA)	%	%	0.60
Selenium (μg/d)			0.85
Selenium (%RDA)	%	%	0.85

Exacerbations during interventions
Duration (days)			0.49

Results are expressed as . Definition of abbreviations: PR: pulmonary rehabilitation; : symptom-limited oxygen uptake; VT: ventilatory threshold; RDA: Recommended Dietary Allowances and Adequate Intakes.