A Protective Role of Paeoniflorin in Fluctuant Hyperglycemia-Induced Vascular Endothelial Injuries through Antioxidative and Anti-Inflammatory Effects and Reduction of PKC<i>β</i>1

<div>Effects of paeoniflorin (PF) on endothelial injury, inflammatory factors, and oxidative stress levels in rats fed with different diets for 4 weeks. Rats in the SHG and IHG groups were fed with low and high glycemic diet, respectively. von Willebrand factor (VWF) (a), sE-selectin (b), TNF-<i>α</i> (c), PECAM-1 (d), AOPPs (e), and T-AOC (f) levels were determined in the various groups. 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Cont: control; SHG: stable high blood glucose; IHG: intermittent high blood glucose; MH: metformin hydrochloride.</div>

Oxidative Medicine and Cellular Longevity

fig6

Figure 6

Figure 6: A Protective Role of Paeoniflorin in Fluctuant Hyperglycemia-Induced Vascular Endothelial Injuries through Antioxidative and Anti-Inflammatory Effects and Reduction of PKC<i>β</i>1 

Figure 6 | A Protective Role of Paeoniflorin in Fluctuant Hyperglycemia-Induced Vascular Endothelial Injuries through Antioxidative and Anti-Inflammatory Effects and Reduction of PKCβ1 