Ethanolic Extract of Senna velutina Roots: Chemical Composition, In Vitro and In Vivo Antitumor Effects, and B16F10-Nex2 Melanoma Cell Death Mechanisms

Table 1

ESVR chemical profile as analyzed by UFLC-MS (negative mode).

Peak	Retention time	UV	Molecular formula	(M-H)	PPM error	MS/MS	Compound
1	1.1	—	C12H20O11	341.1086	0.6	341: 179	Sugar derivative
2	4.2	270	C15H14O7	305.0657	3.2	305: 261, 221, 219, 179, 167, 165	Gallocatechin
3	8.6	270	C15H14O8	305.0660	2.3	305: 261, 221, 219, 179, 167, 165	Epigallocatechin
4	9.1	280	C15H14O9	289.0709	3.0	289: 245, 205, 203	Catechin
5	12.5	280	C15H14O10	289.0714	1.3	289: 245, 205, 203	Epicatechin
6, 7, 8	12.5/13.5/14.6	278	C30H26O11	561.1402/561.1402	1.1	561: 407, 305, 177, 165	Butiniflavan-(epi)gallocatechin
9, 10	16.1/17.6	280	C30H26O10	545.1453/545.1445	0.7	545: 391, 289, 245	Butiniflavan-(epi)catechin
11	18	289/321	C14H12O4	243.0662	0.3	243: 201, 159	Piceatannol
12, 13, 14, 15	19.6/20/20.4/20.7	280	C30H26O10	545.1441	2.3	545: 305, 239, 165	Cassiaflavan-(epi)gallocatechin
16, 17, 18, 19, 20	22.2/22.7/23.2/23.5/24.9	280	C30H26O9	529.1488	3.0	529: 289, 245, 239, 203	Cassiaflavan-(epi)catechin
21	36.1	279/320/406	C34H34O12	633.1992	2.2	633: 615, 597, 579, 557, 555, 539, 317, 299, 298, 259	Dimeric tetrahydroanthracene derivative