Chemical Composition, Antimicrobial Activity, and Antioxidant Activity of Ocotea minarum (Nees & Mart.) Mez.
Table 2
Minimum inhibitory concentration (MIC) and minimal fungicide concentration (MFC) of the bark and leaf extracts of O. minarum against yeasts (μg/mL).
Microorganism
EEB
EAEB
HEEB
HYEB
EEL
EAEL
HEEL
HYEL
FLU
MIC
MFC
MIC
MFC
MIC
MFC
MIC
MFC
MIC
MFC
MIC
MFC
MIC
MFC
MIC
MFC
MIC
Candida albicans
>1000
>1000
>1000
>1000
1000
>1000
>1000
>1000
1000
>1000
>1000
>1000
>1000
>1000
>1000
>1000
2
Candida glabrata
>1000
>1000
>1000
>1000
500
500
>1000
>1000
500
>1000
500
500
>1000
>1000
>1000
>1000
8
Candida krusei
500
>1000
250
>1000
250
250
250
>1000
250
500
125
>1000
>1000
>1000
125
250
32
Candida tropicalis
500
1000
1000
>1000
250
250
1000
>1000
>1000
>1000
500
>1000
>1000
>1000
1000
1000
1
Candida parapsilosis
250
>1000
1000
>1000
500
500
>1000
>1000
250
>1000
500
>1000
>1000
>1000
>1000
>1000
2
Candida dubliniensis
500
1000
250
>1000
1000
>1000
>1000
>1000
250
1000
500
500
>1000
>1000
>1000
>1000
0.25
Cryptococcus gattii
500
>1000
1000
>1000
250
>1000
>1000
>1000
500
>1000
250
>1000
>1000
>1000
>1000
>1000
8
Cryptococcus neoformans
500
>1000
500
>1000
62.5
>1000
>1000
>1000
500
>1000
125
>1000
>1000
>1000
>1000
>1000
8
Rhodotorula glutinis
>1000
>1000
>1000
>1000
>1000
>1000
>1000
>1000
>1000
>1000
>1000
>1000
>1000
>1000
>1000
>1000
32
Rhodotorula mucilaginosa
>1000
>1000
>1000
>1000
>1000
>1000
>1000
>1000
>1000
>1000
>1000
>1000
>1000
>1000
>1000
>1000
32
EEB: ethanolic extract of bark; EAEB: ethyl acetate extract of bark; HEEB: hexane extract of bark; HYEB: hydroalcoholic extract of bark; EEL: ethanolic extract of leaf; EAEL: ethyl acetate extract of leaf; HEEL: hexane extract of leaf; HYEF: hydroalcoholic extract of leaf; FLU: fluconazole. Biological analysis was performed in duplicate with three independent experiments.
