Research Article

Antioxidant Effects of Oral Ang-(1-7) Restore Insulin Pathway and RAS Components Ameliorating Cardiometabolic Disturbances in Rats

Table 2

Nutritional, biometric, and biochemical parameters of rats fed with a control diet or high-fat diet for 13 weeks and treated with HPβCD or HPβCD/Ang-(1-7) during the last 6 weeks of the diet.

ParametersExperimental groups
CT dietFAT diet
HPβCDHPβCD/Ang-(1-7)HPβCDHPβCD/Ang-(1-7)

Food intake (g)
Caloric intake (kcal)
Liver (g/100 g rat mass)
Gastrocnemius (g/100 g rat mass)
Adiposity index#
Body mass (g)#
Fasting glucose (mg/dL)
Total cholesterol (mg/dL)
LDL cholesterol (mg/dL)#
HDL cholesterol (mg/dL)
Triglycerides (mg/dL)#
ALT (U/L)
AST (U/L)
7777

compared to CT-HPβCD/empty group; # compared to HF-HPβCD/empty group (two-way ANOVA followed by Bonferroni test), expressed as of the mean.  = number of animals.