Carnosol Improved Lifespan and Healthspan by Promoting Antioxidant Capacity in Caenorhabditis elegans

Figure 1

Effects of carnosol treatment on ROS accumulation. (a) ROS levels were significantly reduced after 96 hours of treatment with different concentrations of carnosol, showing a U-shaped dose-response curve. (b) The ROS accumulation in the worms pretreated for 96 hours after exposure to or without exposure to 10 mM paraquat for 24 hours. Carnosol decreased the ROS accumulation of C. elegans under normal and paraquat-induced oxidative stress conditions.

(a)

(b)