Oxidative Medicine and Cellular Longevity / 2019 / Article / Fig 1

Research Article

Hepatoprotective Effects of Morchella esculenta against Alcohol-Induced Acute Liver Injury in the C57BL/6 Mouse Related to Nrf-2 and NF-κB Signaling

Figure 1

The hepatoprotective effects of ME in mice with acute alcohol injury. Mice were treated with 13 g/kg of alcohol and/or cotreated with 60 mg/kg of Sil or 200, 400, or 800 mg/kg of ME for 14 days. Histopathological analysis of (a) liver and (b) kidney analyzed with H&E staining (40x). In livers, arrows showed the inflammation infiltration and the fat droplet. In kidneys, arrows showed the inflammation infiltration and the swelling glomerulus. ME and Sil reduced the levels of (c) TG and (d) TC and (e) increased the levels of HDL in the livers of mice with alcohol-induced acute liver injury. Data are expressed as (). # vs. control mice, , , and vs. alcohol only treated mice. ME: M. esculenta, Sil: silybin.

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