Andrographolide Derivative AL-1 Ameliorates Dextran Sodium Sulfate-Induced Murine Colitis by Inhibiting NF-κB and MAPK Signaling Pathways

Figure 5

AL-1 inhibits NF-κB and MAPK activation in DSS-induced UC mice. Western blots and related quantification of p-p65, p-IκBα, iNOS, COX-2, p-p38, p-ERK, and p-JNK expressed as percent of control. All data are presented as for . and compared with the control group and ^#, ^##, and ^### compared with the vehicle-treated UC model group.

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)

(i)