Oxidative Medicine and Cellular Longevity / 2019 / Article / Fig 1

Research Article

Myricetin Alleviates Pathological Cardiac Hypertrophy via TRAF6/TAK1/MAPK and Nrf2 Signaling Pathway

Figure 1

Myr treatment attenuated cardiac hypertrophy and fibrosis. (a) Gross image of the heart; (b) calculated cardiomyocyte across the area of HE staining; (c) Myr prevented the downregulation of α-MHC; (d) Myr inhibited the expression of ANP, BNP, and β-MHC; (e) Myr inhibited interstitial and perivascular fibrosis in mouse heart; (f) calculated LV collagen volume of PSR staining; (g) Myr inhibited the expression of fibrosis-associated markers, for staining experiments, for mRNA determination, versus the CON group or the Myr group, # versus the AB+Myr group.