Oxidative Medicine and Cellular Longevity / 2019 / Article / Fig 3

Research Article

Myricetin Alleviates Pathological Cardiac Hypertrophy via TRAF6/TAK1/MAPK and Nrf2 Signaling Pathway

Figure 3

Myr inhibited cardiac hypertrophy and fibrosis after Nrf2 knockdown. (a) Myr inhibited mouse heart and cardiomyocyte hypertrophy; (b) calculated cardiomyocyte across the area of HE staining; (c) Myr inhibited the expression of ANP, BNP, and β-MHC; (d) Myr inhibited interstitial and perivascular fibrosis in mouse heart; (e) calculated LV collagen volume of PSR staining; (f) Myr inhibited the expression of fibrosis-associated markers, for staining experiments, for mRNA determination, versus the scram group or the scram+Myr group, # versus the shRNA+AB group.