Bucindolol Modulates Cardiac Remodeling by Attenuating Oxidative Stress in H9c2 Cardiac Cells Exposed to Norepinephrine

Figure 3

Cell death analysis by propidium iodide (PI) staining in H9c2 cardiac cells treated with norepinephrine (10 μM) for 24 h, followed by 8 h of bucindolol (10 μM). PI shows the percent of dead cells (c). Representative dot plots indicating the cell populations of all groups (a). Representative histogram indicating FL-2 fluorescence versus cell counts shown in (b). Values expressed as from 3-4 independent experiments (b). Two-way ANOVA followed by Tukey: ^B vs. Norepinephrine Untreated (NE), Control+Bucindolol (CTL+BCD) and Norepineprine+Bucindolol (NE+BCD) vs. CTL and NE.

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(b)

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