Dietary Glycotoxins Impair Hepatic Lipidemic Profile in Diet-Induced Obese Rats Causing Hepatic Oxidative Stress and Insulin Resistance

<div>GC-FID analysis of FAME shows increased levels of esterified fatty acids in HFD, but not in HFDMG rats (a). Determination of fatty acyl methyl esters by GC-FID revealed increased 18 : 1 levels in HFD but not in HFDMG rats, as well as a further increase of 18 : 0 in HFDMG rats and decreased polyunsaturated fatty acids in both groups (b). Increased total saturated fatty acyl chains and decreased monounsaturated fatty acyl chains were observed in the HFDMG group (c), as well as decreased unsaturated/saturated ratio (d). Ct: Wistar 12 m; MG: Wistar + MG supplementation; HFD: HF diet-fed Wistar; HFDMG: HF diet-fed Wistar + MG supplementation. 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Oxidative Medicine and Cellular Longevity

fig3

Figure 3

Figure 3: Dietary Glycotoxins Impair Hepatic Lipidemic Profile in Diet-Induced Obese Rats Causing Hepatic Oxidative Stress and Insulin Resistance 