Subchronic Exposure to Cadmium Causes Persistent Changes in the Reproductive System in Female Wistar Rats

Table 2

Endometrial epithelium thickness (μm) after subchronic oral exposure to CdCl₂ or 17β-estradiol (E₂) exposure and 90- and 180-day postexposure periods in comparison to controls.

Groups	Endometrial epithelium thickness (μm)
	Pure control	0.09 mgCd/kg	0.9 mgCd/kg	1.8 mgCd/kg	4.5 mgCd/kg	Oil control	Positive control
A—90-day exposure		^a,c	^c	^c	^c		^b
B—90-day postexposure period		^c	^c	^c	^c		^b
C—180-day postexposure period		^c	^c	^a,b,c	^a,b,c		^b

All values are expressed as . ^a, significantly different from pure control animals. ^b, significantly different from oil control. ^c, significantly different from positive control.