Research Article

Triptolide Inhibits Preformed Fibril-Induced Microglial Activation by Targeting the MicroRNA155-5p/SHIP1 Pathway

Figure 4

T10 suppressed NF-κB activity via the PI3K/Akt pathway. (a) Immunofluorescence staining of NF-κB. Scale . (b-g) Treatment of T10 did not affect the expressions of IRAK1 and TRAF6, but could downregulate phosphorylation of PI3K, Akt, IKKα/β, and NF-κB. The values were expressed as . and .