Triptolide Inhibits Preformed Fibril-Induced Microglial Activation by Targeting the MicroRNA155-5p/SHIP1 Pathway

<div>The role of SHIP1 in the release of TNF<i>α</i> and IL-1<i>β</i> inhibited by miR155-5p in primary microglia. (a) Expression of SHIP1 after treatment of miR155-5p mimics or inhibitors in primary microglia. (b-e) Levels of SHIP1, TNF<i>α</i>, and IL-1<i>β</i> after treatment of miR155-5p inhibitors in SHIP1 silenced primary microglia. 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Oxidative Medicine and Cellular Longevity

fig7

Figure 7

Figure 7: Triptolide Inhibits Preformed Fibril-Induced Microglial Activation by Targeting the MicroRNA155-5p/SHIP1 Pathway 