Tetrahydrocurcumin Ameliorates Diabetic Cardiomyopathy by Attenuating High Glucose-Induced Oxidative Stress and Fibrosis via Activating the SIRT1 Pathway

Figure 2

THC reduces high glucose-induced ROS via activating the SIRT1 pathway in H9c2 cells. (a) Representative images of DCFH-DA staining (). (b) DCFH-DA intensity. (c) Representative blots of SIRT1, Ac-SOD2, SOD2, and β-actin. (d–f) Histogram shows the quantitative expression changes of SIRT1, Ac-SOD2, and SOD2; all of the proteins were normalized to β-actin before relative quantitative analysis, and all experiments were repeated 4 times independently. Data are presented as . ^/ versus the LG group; ^#/## versus the HG group.

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