Prooxidative Activity of Celastrol Induces Apoptosis, DNA Damage, and Cell Cycle Arrest in Drug-Resistant Human Colon Cancer Cells
Impact of celastrol on the intracellular ROS level (DCF-DA assay) (a) and the mitochondrial H2O2 level (MitoPY assay) (b) in LOVO/DX cell cultures. The results obtained in the presence of celastrol () were compared to the relevant control (), i.e., cells incubated in the presence of the solvent (DMSO). The values are expressed as the ,,,.
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