Physical Exercise Attenuates Oxidative Stress and Morphofunctional Cerebellar Damages Induced by the Ethanol Binge Drinking Paradigm from Adolescence to Adulthood in Rats

Figure 1

Sample description and experimental stages. (a) Description of the sample and division of experimental groups of treadmill physical exercise and ethanol (EtOH) or distilled water (H₂Od) administration. (b) The behavioral assays: open field and beam walking tests. (c) Cerebellum collection for analyses. (d) Oxidative balance analyses through Trolox equivalent antioxidant capacity (TEAC), reduced glutathione (GSH), lipid peroxidation (LPO), and nitrite levels (nitrite). (e) Histological analysis by quantification of Purkinje cells (PC) and immunohistochemically evaluation through anti-synaptophysin (SYP) and anti-myelin basic protein (MBP).