Total Polysaccharides of Lily Bulb Ameliorate Menopause-Like Behavior in Ovariectomized Mice: Multiple Mechanisms Distinct from Estrogen Therapy

<div>Volcano plot and validation of proteomics results and a diagrammatic illustration summarizing the potential mechanisms of TPLB. Volcano plots of three comparison groups: OVX vs. sham (a), TPLB vs. OVX (b), and E<sub>2</sub> vs. OVX (c) with red representing upregulated proteins and green indicating downregulated proteins. (d) Representative images indicating the expression levels of Ras, p-Akt, Akt, p-ERK, ERK, p-CREB, and CREB in the prefrontal cortex; (e) a diagrammatic illustration summarizing the potential mechanisms of TPLB on the menopause-associated psychiatric disorders.</div>

Oxidative Medicine and Cellular Longevity

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Figure 10

Figure 10: Total Polysaccharides of Lily Bulb Ameliorate Menopause-Like Behavior in Ovariectomized Mice: Multiple Mechanisms Distinct from Estrogen Therapy 

Figure 10 | Total Polysaccharides of Lily Bulb Ameliorate Menopause-Like Behavior in Ovariectomized Mice: Multiple Mechanisms Distinct from Estrogen Therapy 