Antiaging, Stress Resistance, and Neuroprotective Efficacies of Cleistocalyx nervosum var. paniala Fruit Extracts Using Caenorhabditis elegans Model

Figure 5

C. nervosum extracts could activate the antioxidant potential by reducing the level of ROS in C. elegans. (a) Relative fluorescence intensity comparison of nematodes exposed to UV-A for 4 h to induce stress along with co- and posttreatment with CMK-P and LMK-P extract at 20 and 30 μg/ml showing significant () reduction in fluorescence when compared to control worms exposed to UV-A without any extract treatment (). (b) Representative image of the negative control worm which was not exposed to UV-A and did not receive any extract treatment. (c) Representative image of the positive control worm which was exposed to UV-A for 4 h but did not receive any extract treatment. (d) Representative image of the worm which was treated with 20 μg/ml of CMK-P along with UV-A exposure for 4 h (cotreatment). (e) Representative image of the worm which was treated with 30 μg/ml of CMK-P along with UV-A exposure for 4 h (cotreatment). (f) Representative image of the worm which was treated with 20 μg/ml of CMK-P after UV-A exposure for 4 h (posttreatment). (g) Representative image of the worm which was treated with 30 μg/ml of CMK-P after UV-A exposure for 4 h (posttreatment). (h) Representative image of the worm which was treated with 20 μg/ml of LMK-P along with UV-A exposure for 4 h (cotreatment). (i) Representative image of worm which was treated with 30 μg/ml of LMK-P along with UV-A exposure for 4 h (cotreatment). (j) Representative image of the worm which was treated with 20 μg/ml of LMK-P after UV-A exposure for 4 h (posttreatment). (k) Representative image of the worm which was treated with 30 μg/ml of LMK-P after UV-A exposure for 4 h (posttreatment).

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