Methane Alleviates Acetaminophen-Induced Liver Injury by Inhibiting Inflammation, Oxidative Stress, Endoplasmic Reticulum Stress, and Apoptosis through the Nrf2/HO-1/NQO1 Signaling Pathway

Figure 2

MRS reduced the expression of inflammatory mediators regulated by NF-κB signaling after APAP challenge. (a–c) Serum levels of TNF-α, IL-6, and IL-10; (d–f) mRNA expression levels of TNF-α, IL-6, and IL-10; (g, h) western blot results of TNF-α and IL-6 expression; (i, j) western blot analysis showing p65 and p-p65 expression in the liver (, , , and ).

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