The Alexipharmic Mechanisms of Five Licorice Ingredients Involved in CYP450 and Nrf2 Pathways in Paraquat-Induced Mice Acute Lung Injury

Figure 16

Effects of the five compounds on CYP3A4 expression in HepG2 cells. (a) HepG2 cells were incubated with 10 μM GLL, LCA, LIA, and ILF and 50 μM 18β-GA for 24 h. CYP3A4 protein expression was measured by western blotting. (b) Data points and error bars represent the of at least three experiments () for each concentration tested; ().

(a)

(b)