TRPV1 and TRPA1 in Lung Inflammation and Airway Hyperresponsiveness Induced by Fine Particulate Matter (PM2.5)
Mean percentage increase in lung resistance () to increasing concentrations of acetylcholine (ACh) (a, b). compared with A967079+PBS mice and and compared with PBS+PM2.5 mice (a). ,, and compared with AMG9810+PM2.5 mice, compared with A967079+PM2.5 mice, and compared with AMG9810+A967079+PM2.5 mice (b). -logPC200 was measured as an indicator of bronchial responsiveness. Individual and mean -logPC200 (c). Individual and mean airway resistance at 256 mg/L of acetylcholine (ACh) (d). ,, and compared with PBS+PM2.5 mice.