N-Acetyltransferase 10 Enhances Doxorubicin Resistance in Human Hepatocellular Carcinoma Cell Lines by Promoting the Epithelial-to-Mesenchymal Transition

Figure 6

Inhibition of NAT10 reverses the hypoxia-induced EMT in HCC cell lines. (a, b) CCK-8 assay of Huh-7 and BEL-7402 cell viability treated with doxorubicin, remodelin, or doxorubicin plus remodelin under hypoxic conditions. (c) Western blotting analysis of E-cadherin and vimentin expression in Huh-7 and BEL-7402 cells subjected to hypoxic conditions. (c) Immunofluorescence analysis of E-cadherin and vimentin expression.

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