N-Acetyltransferase 10 Enhances Doxorubicin Resistance in Human Hepatocellular Carcinoma Cell Lines by Promoting the Epithelial-to-Mesenchymal Transition

Table 2

IC₅₀ values and statistical analyses of doxorubicin (DOX) and remodelin (Remo) treatments in HCC cell lines under hypoxia condition.

	IC50^a
	DOX	Remo	Dox+Remo	Combination index
Huh7	4.327 (0.6257-8.029)	Value too large	Dox 0.9489 (0.6332-1.265); Remo 9.489 (6.332-12.65)	0.22
BEL-7402	1.171 (0.7159-1.626)	Value too large	Dox 0.6343 (0.4754-0.7933); Remo 6.343 (4.754-7.933)	0.54

^aIC₅₀ values show doxorubicin (μg/mL) and remodelin concentration (μM) (concentration, mean (95% confidence intervals)).