Research Article

New Insights into the Hepcidin-Ferroportin Axis and Iron Homeostasis in iPSC-Derived Cardiomyocytes from Friedreich’s Ataxia Patient

Figure 2

Evaluation of the FRDA-like phenotype in iPSCs and CMs. qRT-PCR of FXN gene expression in both CTR and FRDA iPSCs and CMs. Data were normalized with two housekeeping genes, β-actin and GAPDH; the normalized FXN expression value of CTR iPSCs was set to 1, and all other gene expression data were reported to that sample. Data are from four independent differentiation experiments and are expressed as . ; .