New Insights into the Hepcidin-Ferroportin Axis and Iron Homeostasis in iPSC-Derived Cardiomyocytes from Friedreich’s Ataxia Patient

Figure 3

Gene expression of proteins involved in iron homeostasis in CTR and FRDA CMs. Expression levels of TFRC, HAMP, FPN, ATOH8, and FTH1 genes in CTR and FRDA CMs evaluated by qRT-PCR. Data were normalized with two housekeeping genes, β-actin and GAPDH; for each gene, the normalized expression value of CTR CMs was set to 1, and all other gene expression data were reported to that sample. Data are from four independent differentiation experiments and are expressed as mean ± SEM. .