Antiepileptic Effects of Protein-Rich Extract from Bombyx batryticatus on Mice and Its Protective Effects against H₂O₂-Induced Oxidative Damage in PC12 Cells via Regulating PI3K/Akt Signaling Pathways

Figure 5

Effects of BBPs on ROS levels of H₂O₂-stimulated PC12 cells. (a) Normal group. (b) Model group. (c) 200 μg/mL of BBP group. (d) 400 μg/mL of BBP group. (e) 800 μg/mL of BBP group. (f) Fluorescence intensity of different groups. PC12 cells were treated with BBPs at concentrations of 200, 400, and 800 μg/mL for 24 h, subsequently subjected to H₂O₂ at the concentration of 300 μmol/L for 4 h. The intracellular ROS level by the flow cytometry (FCM) assay. BBPs: protein extracts in Bombyx batryticatus. The values represent (). vs. the normal group; and vs. the model group.

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