Protection against Doxorubicin-Induced Cytotoxicity by Geniposide Involves AMPKα Signaling Pathway

Figure 1

GE improved cardiac function and alleviated cardiac injury in mice with DOX treatment. (a) Body weight of four groups (). (b) Statistical results of the heart weight (HW)/tibia length (TL) (). (c) Heart rate of mice in four groups. (d) Maximum pressure. (e) Ejection fraction (EF) of mice (). (f, g) Hemodynamic analysis of mice with or without GE treatment (). (h) The mRNA expressions of hypertrophic markers (). (i) Plasma cardiac troponin-I (cTnI) levels. (j, k) Levels of creatine kinase (CK) and lactate dehydrogenase (LDH). Values represent the . versus saline, versus DOX.

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